The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration
نویسندگان
چکیده
منابع مشابه
The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration.
Senescence is a form of cell cycle arrest induced by stress such as DNA damage and oncogenes. However, while arrested, senescent cells secrete a variety of proteins collectively known as the senescence-associated secretory phenotype (SASP), which can reinforce the arrest and induce senescence in a paracrine manner. However, the SASP has also been shown to favor embryonic development, wound heal...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2017
ISSN: 0890-9369,1549-5477
DOI: 10.1101/gad.290635.116